High-resolution Computed Tomography for Clinical Imaging of Bone Microarchitecture

High-resolution Computed Tomography for Clinical Imaging of Bone Microarchitecture

BACKGROUND The role of bone structure, one component of bone quality, has emerged as a contributor to bone strength. The application of high-resolution imaging in evaluating bone structure has evolved from an in vitro technology for small specimens to an emerging clinical research tool for in vivo studies in humans. However, many technical and practical challenges remain to translate these tech...

In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography.

CONTEXT Assessment of trabecular microarchitecture may enhance the prediction of fracture risk and improve monitoring of treatment response. A new high-resolution peripheral quantitative computed tomography (HR-pQCT) system permits in vivo assessment of trabecular architecture and volumetric bone mineral density (BMD) at the distal radius and tibia with a voxel size of 82 microm3. OBJECTIVE A...

High Resolution Computed Tomography

High Resolution Computed Tomography

High-resolution computed tomography

This paper investigates high-resolution reconstructions from eeciently sampled data in parallel-beam tomography, in particular local tomography. A class of sampling schemes is deened and characterized, and it is shown that the standard scheme and the interlaced scheme of Cormack are most promising. An error analysis for the ltered backprojection algorithm for both global and local tomography is...